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Massive crystal-storing histiocytosis associated with low-grade malignant B-cell lymphoma of MALT-type of the parotid gland.
- Source :
-
Diagnostic cytopathology [Diagn Cytopathol] 1997 Aug; Vol. 17 (2), pp. 148-52. - Publication Year :
- 1997
-
Abstract
- Massive crystal deposition is unusual in lymphoproliferative disorders. In this report, a mucosa-associated lymphoid tissue (MALT) low-grade B-cell lymphoma of the parotid gland containing large numbers of crystal-storing histiocytes is described. The patient, an 81-yr-old female, presented with a history of long-standing left parotid gland enlargement. FNA cytology of the tumor showed a lymphoplasmacytic infiltrate and sheets of large benign histiocytes with abundant eosinophilic intracytoplasmic inclusions. Paraffinsection immunohistochemistry performed on the cell block demonstrated that the histiocytic cells were immunoreactive for the KP-1 (CD-68) antibody and monotypic for cytoplasmic IGM and L-light chain. The cytological diagnosis was consistent with a low-grade B-cell lymphoma with plasmacytic differentiation associated with crystal-storing histiosis. A periparotid lymph node was biopsied and showed involvement by a monocytoid B-cell lymphoma with plasmacytic differentiation and crystal-storing histiocytosis in the pericapsular region.
- Subjects :
- Aged
Aged, 80 and over
Antigens, CD analysis
Antigens, Differentiation, Myelomonocytic analysis
Biopsy, Needle
Crystallization
Female
Histiocytes chemistry
Histiocytes pathology
Histiocytosis complications
Histiocytosis metabolism
Humans
Immunoglobulin Light Chains analysis
Immunoglobulin M analysis
Immunohistochemistry
Lymphoma, B-Cell, Marginal Zone chemistry
Parotid Neoplasms chemistry
Histiocytosis pathology
Lymphoma, B-Cell, Marginal Zone pathology
Parotid Neoplasms pathology
Subjects
Details
- Language :
- English
- ISSN :
- 8755-1039
- Volume :
- 17
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Diagnostic cytopathology
- Publication Type :
- Academic Journal
- Accession number :
- 9258624
- Full Text :
- https://doi.org/10.1002/(sici)1097-0339(199708)17:2<148::aid-dc12>3.0.co;2-g