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Bioactive saponins and glycosides. X. On the constituents of zizyphi spinosi semen, the seeds of Zizyphus jujuba Mill. var. spinosa Hu (1): structures and histamine release-inhibitory effect of jujubosides A1 and C and acetyljujuboside B.
- Source :
-
Chemical & pharmaceutical bulletin [Chem Pharm Bull (Tokyo)] 1997 Jul; Vol. 45 (7), pp. 1186-92. - Publication Year :
- 1997
-
Abstract
- New dammarane-type triterpene oligoglycosides, jujubosides A1 and C and acetyljujuboside B1 were isolated from Zizyphi Spinosi Semen, the seeds of Zizyphus jujuba MILL. var. spinosa Hu, together-with three known saponins. The structures of jujubosides A1 and C and acetyljujuboside B were determined on the basis of chemical and physicochemical evidence. Jujubosides A1 and C and acetyljujuboside B were found to inhibit the histamine release from rat peritoneal exudate cells induced by antigen-antibody-reaction.
- Subjects :
- Animals
Ascitic Fluid cytology
Carbohydrate Sequence
Glycosides isolation & purification
Histamine Release drug effects
Male
Molecular Conformation
Molecular Sequence Data
Plant Extracts isolation & purification
Rats
Rats, Wistar
Seeds chemistry
Structure-Activity Relationship
Glycosides chemical synthesis
Glycosides pharmacology
Histamine Antagonists chemistry
Histamine Antagonists pharmacology
Plant Extracts pharmacology
Plants, Medicinal chemistry
Saponins chemistry
Saponins pharmacology
Subjects
Details
- Language :
- English
- ISSN :
- 0009-2363
- Volume :
- 45
- Issue :
- 7
- Database :
- MEDLINE
- Journal :
- Chemical & pharmaceutical bulletin
- Publication Type :
- Academic Journal
- Accession number :
- 9246753
- Full Text :
- https://doi.org/10.1248/cpb.45.1186