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[The use of propofol in carotid surgery].
[The use of propofol in carotid surgery].
- Source :
-
Revista espanola de anestesiologia y reanimacion [Rev Esp Anestesiol Reanim] 1997 Apr; Vol. 44 (4), pp. 144-9. - Publication Year :
- 1997
-
Abstract
- Objective: To compare two anesthetic techniques in carotid surgery. The first technique was propofol in continuous perfusion throughout the procedure (group A) and the other used etomidate for anesthetic induction and isoflurane for maintenance (group B).<br />Patients and Methods: The patients were assigned randomly either to group A (n = 23) to receive propofol in continuous perfusion for induction (0.8-1 mg/kg) and for maintenance (4-6 mg/kg/h) or to group B (n = 25) to receive etomidate (0.25 mg/kg) for induction and isoflurane 0.6-0.8% for maintenance. Ventilation was maintained with O2/N2O. Systolic and diastolic arterial pressures (SAP and DAP) and heart rate were measured at baseline, during induction (minutes 1, 2, 3, 5 and 10), immediately before and 1 minute after interruption of carotid flow, once flow had been released and after extubation. Other variables recorded were time until awakening and extubation, presence of pain, degree of well-being, need for analgesics and vasodilators, perioperative complications and time until hospital release.<br />Results: The variations in hemodynamic parameters during induction and during maintenance were similar for both techniques. Orotracheal intubation increased SAP in both groups. Time until eye opening and awakening were shorter in group A but the difference was not statistically significant.<br />Conclusions: The use of propofol for induction and maintenance during carotid surgery was as safe as conventional anesthetic technique with etomidate and isoflurane.
- Subjects :
- Aged
Anesthesia, Inhalation adverse effects
Anesthetics, Inhalation adverse effects
Double-Blind Method
Etomidate adverse effects
Female
Humans
Isoflurane adverse effects
Male
Middle Aged
Anesthesia, Intravenous adverse effects
Anesthetics, Intravenous adverse effects
Carotid Arteries surgery
Propofol adverse effects
Subjects
Details
- Language :
- Spanish; Castilian
- ISSN :
- 0034-9356
- Volume :
- 44
- Issue :
- 4
- Database :
- MEDLINE
- Journal :
- Revista espanola de anestesiologia y reanimacion
- Publication Type :
- Academic Journal
- Accession number :
- 9244941