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The increasing burden of disease in Bangladeshi children due to Haemophilus influenzae type b meningitis.
- Source :
-
Annals of tropical paediatrics [Ann Trop Paediatr] 1997 Mar; Vol. 17 (1), pp. 5-8. - Publication Year :
- 1997
-
Abstract
- A laboratory-based study of diagnosed bacterial meningitis in the national paediatric hospital identified 852 cases of meningitis in the 8-year period 1987-1994. There were 587 culture-positive cases, of which Haemophilus influenzae (47%) and Streptococcus pneumoniae (32%) accounted for 80%. H. influenzae showed a remarkable increase of 700% during the study period. Most of the H. influenzae cases (90%) occurred in the 1st 2 years of life. Analysis of culture-negative specimens by antigen detection in the last 2 years also revealed the predominance of H. influenzae (71.4%) and S. pneumoniae (22.4%). Typing of H. influenzae isolates during this time showed that 98% of the strains were type b. This retrospective hospital-based study indicated a pronounced increase in the incidence of H. influenzae meningitis and strongly supports the need for large-scale Hib vaccination for young children. However, such nationwide intervention will probably need to be based on a prospective on a prospective and population-based surveillance of H. influenzae infections.
- Subjects :
- Age Distribution
Bangladesh epidemiology
Child
Child, Preschool
Humans
Infant
Infant, Newborn
Meningitis, Bacterial cerebrospinal fluid
Meningitis, Bacterial microbiology
Meningitis, Haemophilus cerebrospinal fluid
Meningitis, Haemophilus microbiology
Meningitis, Meningococcal cerebrospinal fluid
Meningitis, Meningococcal microbiology
Pneumococcal Infections cerebrospinal fluid
Pneumococcal Infections microbiology
Retrospective Studies
Meningitis, Bacterial epidemiology
Subjects
Details
- Language :
- English
- ISSN :
- 0272-4936
- Volume :
- 17
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Annals of tropical paediatrics
- Publication Type :
- Academic Journal
- Accession number :
- 9176570
- Full Text :
- https://doi.org/10.1080/02724936.1997.11747855