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Encephalomyelitis subsequent to mycoplasma infection with elevated serum anti-Gal C antibody.
- Source :
-
Pediatric neurology [Pediatr Neurol] 1997 Apr; Vol. 16 (3), pp. 241-4. - Publication Year :
- 1997
-
Abstract
- We report a 7-year-old girl with acute disseminated encephalomyelitis subsequent to a mycoplasma infection. She manifested a prolonged state of akinetic mutism, during which EEG revealed well-synchronized spindles. Four months later, she regained consciousness, with no mental deficit, but complete flaccid quadriplegia persisted and magnetic resonance imaging disclosed extensive destruction of the spinal cord. Antibody against galactocerebroside was detected in her serum during the acute phase. The anti-Gal C antibody is suggested to be involved in the pathogenesis of immune-mediated demyelinating diseases in the central nervous system subsequent to mycoplasma infections.
- Subjects :
- Akinetic Mutism etiology
Child
Electroencephalography
Encephalomyelitis diagnosis
Female
Humans
Magnetic Resonance Imaging
Quadriplegia diagnosis
Quadriplegia etiology
Spinal Cord pathology
Tomography, X-Ray Computed
Antibodies analysis
Encephalomyelitis immunology
Encephalomyelitis microbiology
Galactosylceramides immunology
Mycoplasma Infections
Subjects
Details
- Language :
- English
- ISSN :
- 0887-8994
- Volume :
- 16
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- Pediatric neurology
- Publication Type :
- Academic Journal
- Accession number :
- 9165517
- Full Text :
- https://doi.org/10.1016/s0887-8994(97)89976-6