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The value of hyoscine butylbromide in abdominal MR imaging with and without oral magnetic particles.
- Source :
-
Abdominal imaging [Abdom Imaging] 1997 Jul-Aug; Vol. 22 (4), pp. 381-8. - Publication Year :
- 1997
-
Abstract
- Purpose: The purpose of this article was to assess the impact of intravenous (IV) anticholinergic hyoscine butylbromide in abdominal magnetic resonance (MR) imaging with oral magnetic particles (OMP) [ABDOS-CAN, Ferristene (USAN), Nycomed Imaging AS, Oslo, Norway].<br />Materials and Methods: In 31 patients with abdominal tumors, T1-weighted spin-echo (SE) images (SE 600/ 15; 1.5 T) were obtained without and with IV hyoscine butylbromide (20 mg) before and after administration of 800 ml of OMP. Two blinded readers assessed motion artifacts, bowel-wall visualization, and lesion delineation on the four sets of T1-weighted images. The two-tailed Wilcoxon paired sample test was used for statistical analysis (p < .05).<br />Results: Hyoscine butylbromide reduced motion artifacts and improved bowel-wall visualization on precontrast and OMP-enhanced images at a statistically significant level (p = 0.0006-0.037). The lowest degree of artifacts was recorded on OMP images with hyoscine butylbromide. OMP with hyoscine butylbromide significantly improved lesion delineation compared to studies without antiperistaltic drug before (p = 0.019) and after OMP administration (p = 0.01).<br />Conclusions: The authors conclude that the use of IV hyoscine butylbromide is recommended for OMP-enhanced abdominal MR imaging with T1-weighted SE pulse sequences at 1.5 T.
- Subjects :
- Abdominal Pain chemically induced
Administration, Oral
Adult
Aged
Artifacts
Dextrans
Female
Ferrosoferric Oxide
Humans
Image Enhancement
Injections, Intravenous
Intestines pathology
Magnetite Nanoparticles
Male
Middle Aged
Peristalsis drug effects
Prospective Studies
Safety
Single-Blind Method
Suspensions
Vision Disorders chemically induced
Vomiting chemically induced
Abdominal Neoplasms diagnosis
Butylscopolammonium Bromide administration & dosage
Butylscopolammonium Bromide adverse effects
Contrast Media adverse effects
Iron administration & dosage
Iron adverse effects
Magnetic Resonance Imaging
Muscarinic Antagonists administration & dosage
Muscarinic Antagonists adverse effects
Oxides administration & dosage
Oxides adverse effects
Subjects
Details
- Language :
- English
- ISSN :
- 0942-8925
- Volume :
- 22
- Issue :
- 4
- Database :
- MEDLINE
- Journal :
- Abdominal imaging
- Publication Type :
- Academic Journal
- Accession number :
- 9157855
- Full Text :
- https://doi.org/10.1007/s002619900215