Grapefruits and drugs: when is statistically significant clinically significant?

Authors :: Abernethy DR
Source :: The Journal of clinical investigation [J Clin Invest] 1997 May 15; Vol. 99 (10), pp. 2297-8.
Publication Year :: 1997

Subjects :: Animals
Cytochrome P-450 CYP3A
Cytochrome P-450 Enzyme System metabolism
Felodipine blood
Felodipine pharmacokinetics
Humans
Metabolic Clearance Rate
Nifedipine blood
Nifedipine pharmacokinetics
Oxidoreductases, N-Demethylating metabolism
Smoking
Aryl Hydrocarbon Hydroxylases
Beverages
Citrus
Pharmacokinetics

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