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[Current aspects of acute respiratory distress syndrome in children].

Authors :
Durand P
Le Pommelet C
Orbach D
Devictor D
Huault G
Source :
Archives de pediatrie : organe officiel de la Societe francaise de pediatrie [Arch Pediatr] 1997 Jan; Vol. 4 (1), pp. 61-77.
Publication Year :
1997

Abstract

Acute respiratory distress syndrome (ARDS) is a frequent condition in pediatric intensive care units. The mortality remains high despite advances in conventional mechanical ventilation and aetiological treatment. Several animal studies have documented lung injury during mechanical ventilation with high tidal volume, and clinical investigations have shown that in human ARDS, most ventilation is distributed to the small areas of remaining aerated lung resulting in overdistension of these areas and lung injury ("baby lung" theory). Nevertheless the usefulness of extrapulmonary gas exchange remains much debated. New ventilatory strategies have been developed in order to reduce ventilator-induced lung injury and to improve systemic oxygenation but multicentric randomized clinical trials are needed before these strategies can be validated.

Details

Language :
French
ISSN :
0929-693X
Volume :
4
Issue :
1
Database :
MEDLINE
Journal :
Archives de pediatrie : organe officiel de la Societe francaise de pediatrie
Publication Type :
Academic Journal
Accession number :
9084711
Full Text :
https://doi.org/10.1016/s0929-693x(97)84311-4