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[Cardiomyopathy induced by catecholamines in neuroblastoma].

Authors :
Joseph T
Olivier B
Magnier S
Brugières L
Casasoprana A
Source :
Archives de pediatrie : organe officiel de la Societe francaise de pediatrie [Arch Pediatr] 1997 Jan; Vol. 4 (1), pp. 32-5.
Publication Year :
1997

Abstract

Background: Cardiovascular disorders associated with neural crest tumors are congenital malformations rather than cardiomyopathies.<br />Case Report: A 18 month-old girl developed heart failure one week after discovery of an adrenal neuroblastoma with excessive secretion of catecholamines. Investigation showed dilated cardiomyopathy without myocardial hypertrophy. Besides chemotherapy, the patient was given nitrous derivatives, diuretics and converting enzyme inhibitor. His cardiac condition gradually improved so that partial resection of the tumor was possible 2 years later.<br />Conclusions: The cardiomyopathy presented by this patient is possibly catecholamine-induced even though catecholamines usually results in myocardial hypertrophy rather than dilated cardiomyopathy. The reason why such a cardiomyopathy has never been reported in patients with neuroblastoma remains unclear.

Details

Language :
French
ISSN :
0929-693X
Volume :
4
Issue :
1
Database :
MEDLINE
Journal :
Archives de pediatrie : organe officiel de la Societe francaise de pediatrie
Publication Type :
Academic Journal
Accession number :
9084706
Full Text :
https://doi.org/10.1016/s0929-693x(97)84303-5