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Clinical evidence for hepatitis B transmission resulting from corneal transplantation.
- Source :
-
Cornea [Cornea] 1997 Mar; Vol. 16 (2), pp. 132-7. - Publication Year :
- 1997
-
Abstract
- Purpose: Two cases of hepatitis B virus (HBV) infection after penetrating keratoplasty are presented.<br />Methods: An extensive clinical and serologic investigation of these two transplant recipients was performed. In addition, the medical histories, autopsy reports, and specimens of blood from the two deceased corneal tissue donors were retrieved and studied.<br />Results: Serum from both donors was positive for hepatitis B surface antigen; the clinical history and serologic testing of both recipients strongly suggest that the HBV infection in each case was acquired from donor corneal tissue.<br />Conclusion: To our knowledge, these are the first documented cases of HBV infection after corneal transplantation. Eye banks should continue to screen donors for HBV.
- Subjects :
- Acute Disease
Adult
Aged
Aged, 80 and over
Corneal Diseases diagnosis
DNA, Viral analysis
Eye Banks
Eye Infections, Viral diagnosis
Eye Infections, Viral etiology
Female
Follow-Up Studies
Hepatitis B diagnosis
Hepatitis B virology
Hepatitis B Antibodies analysis
Hepatitis B Core Antigens immunology
Hepatitis B Surface Antigens immunology
Hepatitis B virus genetics
Hepatitis B virus immunology
Hepatitis B virus isolation & purification
Humans
Immunoglobulin M immunology
Male
Middle Aged
Serologic Tests
Tissue Donors
Cornea virology
Corneal Diseases microbiology
Disease Transmission, Infectious
Eye Infections, Viral transmission
Hepatitis B transmission
Keratoplasty, Penetrating adverse effects
Subjects
Details
- Language :
- English
- ISSN :
- 0277-3740
- Volume :
- 16
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Cornea
- Publication Type :
- Academic Journal
- Accession number :
- 9071524