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[Laryngeal mucociliary clearance: influence of beta-2 agonists, beta antagonists, and alpha-agonists. An experimental study in rabbits].
- Source :
-
Acta otorrinolaringologica espanola [Acta Otorrinolaringol Esp] 1996 Nov-Dec; Vol. 47 (6), pp. 425-8. - Publication Year :
- 1996
-
Abstract
- Laryngeal mucociliary clearance was studied in 35 rabbit larynxes in the immediate post mortem period using charcoal powder. Mucociliary currents flowed from the subglottic walls to the posterior commissure. The normal laryngeal mucociliary clearance rate was 3.7 +/- 1.1 mm/min. Salbutamol accelerated mucociliary clearance (p < 0.01). Propranolol significantly reduced the mucociliary clearance rate (p < 0.001). Mucociliary clearance was not observed in any methoxamine-treated larynxes.
- Subjects :
- Adrenergic alpha-Agonists administration & dosage
Adrenergic beta-Agonists administration & dosage
Adrenergic beta-Antagonists administration & dosage
Albuterol administration & dosage
Animals
Methoxamine administration & dosage
Propranolol administration & dosage
Rabbits
Adrenergic alpha-Agonists pharmacology
Adrenergic beta-Agonists pharmacology
Adrenergic beta-Antagonists pharmacology
Albuterol pharmacology
Larynx drug effects
Methoxamine pharmacology
Mucociliary Clearance drug effects
Propranolol pharmacology
Subjects
Details
- Language :
- Spanish; Castilian
- ISSN :
- 0001-6519
- Volume :
- 47
- Issue :
- 6
- Database :
- MEDLINE
- Journal :
- Acta otorrinolaringologica espanola
- Publication Type :
- Academic Journal
- Accession number :
- 9044579