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[The neuroendocrine mechanisms of the development of the anovulatory hyperandrogenic syndrome in rats].
- Source :
-
Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994) [Fiziol Zh (1994)] 1995 Sep-Dec; Vol. 41 (5-6), pp. 33-7. - Publication Year :
- 1995
-
Abstract
- The anovulatory syndrome in adult female rats occurred after subcutaneous implantation of silastic capsules with testosterone. Acceleration of testosterone conversion into estradiol in the hypothalamus, suppression of pituitary LH responsiveness to LHRH, increase of blood plasma bioactive LH, estrous cycle disorder as well as morphological changes in ovaries demonstrate the alterations in neuroendocrine control of ovulation.
- Subjects :
- Animals
Anovulation chemically induced
Anovulation metabolism
Disease Models, Animal
Drug Implants
Estrus drug effects
Female
Gonadotropin-Releasing Hormone administration & dosage
Gonadotropin-Releasing Hormone metabolism
Hyperandrogenism chemically induced
Hyperandrogenism metabolism
Hypothalamus metabolism
Luteinizing Hormone blood
Neurosecretory Systems drug effects
Rats
Syndrome
Testosterone administration & dosage
Testosterone metabolism
Time Factors
Anovulation physiopathology
Hyperandrogenism physiopathology
Neurosecretory Systems physiopathology
Subjects
Details
- Language :
- Ukrainian
- ISSN :
- 2522-9028
- Volume :
- 41
- Issue :
- 5-6
- Database :
- MEDLINE
- Journal :
- Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994)
- Publication Type :
- Academic Journal
- Accession number :
- 9026390