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Specific metabolic effects imposed by Streptococcus pneumoniae upon the response to femoral fracture in the rat.
- Source :
-
The American journal of clinical nutrition [Am J Clin Nutr] 1977 Sep; Vol. 30 (9), pp. 1512-3. - Publication Year :
- 1977
-
Abstract
- The possible potentiation of an infection upon the metabolic consequences of trauma was tested in rats using a 2 X 2 block design which included control, femoral fracture, pneumococcal infection, and fracture plus infection groups. Infection introduced unique metabolic effects different from those of starvation, femoral fracture, or both together. Infection-induced effects included an accelerated conversion of 14C-alanine to glucose, higher serum haptoglobin, alpha2-macrofetoprotein, copper, and ceruloplasmin values, and lower serum iron, zinc, and transferrin concentrations. The first three of these infection-induced effects were diminished in rats with a femoral fracture. No measured effect of infection was increased in traumatized rats.
Details
- Language :
- English
- ISSN :
- 0002-9165
- Volume :
- 30
- Issue :
- 9
- Database :
- MEDLINE
- Journal :
- The American journal of clinical nutrition
- Publication Type :
- Academic Journal
- Accession number :
- 900063
- Full Text :
- https://doi.org/10.1093/ajcn/30.9.1512