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[Wilms tumor and Bloom syndrome].

Authors :
Berger C
Frappaz D
Leroux D
Blez F
Vercherat M
Bouffet E
Jalbert P
Brunat-Mentigny M
Source :
Archives de pediatrie : organe officiel de la Societe francaise de pediatrie [Arch Pediatr] 1996 Aug; Vol. 3 (8), pp. 802-5.
Publication Year :
1996

Abstract

Unlabelled: Bloom syndrome is characterized by growth failure, skin anomalies with sun sensitivity, minor anatomic defects, excessive chromosomic fragility and usually severe immune deficiency. The chromosome fragility predisposes these children to the development of hematologic malignancies and solid tumors.<br />Case Report: Morgan, a 4-year-old boy with Bloom syndrome, developed a Wilms tumor. Chemotherapy was poorly tolerated. Two years later, the child died from an uncontrolled progressive disease.<br />Conclusion: This is the fourth reported case of Wilms tumor occurring in a child with Bloom syndrome. This possibility requires repeated abdominal ultrasonography in such patients.

Details

Language :
French
ISSN :
0929-693X
Volume :
3
Issue :
8
Database :
MEDLINE
Journal :
Archives de pediatrie : organe officiel de la Societe francaise de pediatrie
Publication Type :
Academic Journal
Accession number :
8998536
Full Text :
https://doi.org/10.1016/0929-693x(96)82165-8