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[Insulin resistance and hyperinsulinemia--clinical aspects].
- Source :
-
Przeglad lekarski [Przegl Lek] 1996; Vol. 53 (9), pp. 647-52. - Publication Year :
- 1996
-
Abstract
- A group of metabolic disorders including insulin resistance and hyperinsulinemia, impaired glucose tolerance, visceral obesity, hypertension, dyslipidemia, hyperuricemia, hypercoagulability and microalbuminuria determine the risk for the development of atherosclerosis, coronary artery disease and cerebral vascular disorders. Although available studies on the pathogenesis of the metabolic syndrome are equivocal, it is most frequently hypothesized that hereditary of insulin resistance leads to the remaining metabolic disorders including diabetes mellitus, atherosclerosis and coronary artery disease. Despite pathogenetic controversies, there are convincing arguments for the diagnosis of the metabolic syndrome and search for therapy improving insulin sensitivity and reducing hyperinsulinemia thus preventing the development of diabetes mellitus and coronary artery disease.
- Subjects :
- Arteriosclerosis etiology
Cerebrovascular Disorders etiology
Coronary Disease etiology
Humans
Hyperinsulinism complications
Hyperlipidemias complications
Hypertension complications
Insulin Resistance
Obesity complications
Arteriosclerosis prevention & control
Cerebrovascular Disorders prevention & control
Coronary Disease prevention & control
Hyperinsulinism therapy
Subjects
Details
- Language :
- Polish
- ISSN :
- 0033-2240
- Volume :
- 53
- Issue :
- 9
- Database :
- MEDLINE
- Journal :
- Przeglad lekarski
- Publication Type :
- Academic Journal
- Accession number :
- 8992530