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Different susceptibility of coagulase-positive and coagulase-negative staphylococci to ciprofloxacin.
- Source :
-
The new microbiologica [New Microbiol] 1996 Oct; Vol. 19 (4), pp. 309-14. - Publication Year :
- 1996
-
Abstract
- Ciprofloxacin susceptibility was evaluated in 573 clinical staphylococcal isolates (Staphylococcus aureus 230, methicillin-resistant (MR) 36%; coagulase-negative strains 343, MR 66%) collected from 1989 to 1995. Resistance to ciprofloxacin for MR Staphylococcus aureus was 25% until 1991 when ciprofloxacin was introduced into the hospital formulary, and rose progressively to 90% in 1994-1995. MR Staphylococcus haemolyticus showed a ciprofloxacin resistance of 46% until 1991 and of 73% from 1992 to 1995. In contrast MR Staphylococcus epidermidis and other coagulase-negative strains showed a constant susceptibility to this agent (80%). Ciprofloxacin has limited usefulness against MR Staphylococcus aureus but can be still used to treat Staphylococcus epidermidis infections.
- Subjects :
- Coagulase metabolism
Cross Infection drug therapy
Drug Resistance, Microbial
Humans
Italy
Methicillin Resistance
Staphylococcal Infections drug therapy
Staphylococcus enzymology
Staphylococcus aureus drug effects
Staphylococcus epidermidis drug effects
Time Factors
Ciprofloxacin pharmacology
Staphylococcus drug effects
Subjects
Details
- Language :
- English
- ISSN :
- 1121-7138
- Volume :
- 19
- Issue :
- 4
- Database :
- MEDLINE
- Journal :
- The new microbiologica
- Publication Type :
- Academic Journal
- Accession number :
- 8914131