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Bacterial complications of primary varicella in children.
- Source :
-
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America [Clin Infect Dis] 1996 Oct; Vol. 23 (4), pp. 698-705. - Publication Year :
- 1996
-
Abstract
- Bacterial complications of varicella in 84 patients younger than 16 years of age (48 females; median age, 2.9 years) who required hospitalization between 1985 and 1995 were retrospectively analyzed. The purpose of the study was to describe demographics, clinical manifestations, bacteriology, and factors affecting outcome. Seventy-six percent of patients were younger than 5 years of age. The eldest children in households were significantly underrepresented (P = .00025). Skin infections occurred in 61 patients (73%), and deep-seated infections and/or shock occurred in 23 (27%). The latter complications were significantly associated with thrombocytopenia (P = .011) and bacteremia (P = .014) at the time of admission, prolonged fever (P = .001), prolonged hospitalization (P < .0001), intensive care management (P < .0001), and fatal outcome (P = .019). Group A beta-hemolytic streptococcus (59% of isolates) and Staphylococcus aureus (28%) were the predominant isolates. Before and after 1990, five (31%) of 16 and 13 (62%) of 21 streptococcal complications, respectively, were invasive infections (P = .09). These data underscore the need for universal immunization against chickenpox.
- Subjects :
- Adolescent
Arthritis diagnosis
Arthritis epidemiology
Bacterial Infections epidemiology
Cellulitis diagnosis
Cellulitis epidemiology
Child
Child, Preschool
Empyema diagnosis
Empyema epidemiology
Fasciitis, Necrotizing diagnosis
Fasciitis, Necrotizing epidemiology
Female
Haemophilus Infections diagnosis
Haemophilus Infections epidemiology
Haemophilus influenzae isolation & purification
Humans
Impetigo diagnosis
Impetigo epidemiology
Infant
Male
Myositis diagnosis
Myositis epidemiology
Osteomyelitis diagnosis
Osteomyelitis epidemiology
Pneumonia, Bacterial diagnosis
Pneumonia, Bacterial epidemiology
Retrospective Studies
Risk Factors
Sepsis diagnosis
Sepsis epidemiology
Skin Diseases, Bacterial diagnosis
Skin Diseases, Bacterial epidemiology
Staphylococcal Infections diagnosis
Staphylococcal Infections epidemiology
Staphylococcus aureus isolation & purification
Streptococcal Infections diagnosis
Streptococcal Infections epidemiology
Streptococcus agalactiae isolation & purification
Streptococcus pyogenes isolation & purification
Bacterial Infections diagnosis
Chickenpox complications
Chickenpox microbiology
Subjects
Details
- Language :
- English
- ISSN :
- 1058-4838
- Volume :
- 23
- Issue :
- 4
- Database :
- MEDLINE
- Journal :
- Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
- Publication Type :
- Academic Journal
- Accession number :
- 8909829
- Full Text :
- https://doi.org/10.1093/clinids/23.4.698