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[Effect of acetycholine chloride and chlorocholine chloride on the resting potential and membrane resistance of identified mollusk A and B neurons].

Authors :
Sologub MI
El-Sayed EM
Grupe R
Source :
Biofizika [Biofizika] 1977 May-Jun; Vol. 22 (3), pp. 461-4.
Publication Year :
1977

Abstract

Chlorcholine chloride (CCC) the molecule of which has no other group, characteristic of acetylcholine (Ach), causes an effective cholinomimetic action on the surface membrane of the mollusc neurons A and B. As the concentration of Ach and CCC increases from 10(-6) to 10(-3) M the resting potential (RP) and the membrane resistance (R) of the neuron A first increases then decreases. The increase of Ach and CCC concentration causes in the neuron B only a decrease of the above mentioned parameters. The data point to the necessity of improving the ideas about the structure of cholinoreceptors and mechanism of cholinoreceptor-cholinomimetic interaction.

Details

Language :
Russian
ISSN :
0006-3029
Volume :
22
Issue :
3
Database :
MEDLINE
Journal :
Biofizika
Publication Type :
Academic Journal
Accession number :
889905