IgE, TNF alpha, IL1 beta, IL4 and IFN gamma gene polymorphisms in sheep selected for resistance to fleece rot and flystrike.

Authors :: Engwerda CR
Dale CJ
Sandeman RM
Source :: International journal for parasitology [Int J Parasitol] 1996 Jul; Vol. 26 (7), pp. 787-91.
Publication Year :: 1996
Abstract: Investigation of restriction fragment length polymorphisms (RFLPs) associated with immunoglobulin E (IgE) and cytokine genes in the sheep genome revealed polymorphisms in the IgE constant heavy chain, interferon gamma and interleukin 4 genes. No polymorphisms were found in interleukin 1 beta or tumour necrosis factor alpha. PstI and BamHI RFLPs in the IgE gene showed differences in frequency between animals selected for resistance or susceptibility to fleece rot and blowfly strike.

Subjects :: Animals
Disease Susceptibility
Immunity, Innate
Interferon-gamma genetics
Interleukin-1 genetics
Interleukin-4 genetics
Male
Myiasis immunology
Tumor Necrosis Factor-alpha genetics
Cytokines genetics
Genes, Immunoglobulin
Immunoglobulin E genetics
Myiasis veterinary
Polymorphism, Restriction Fragment Length
Sheep genetics
Sheep Diseases immunology

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