Spontaneous reseal of the fetal membranes in patients with high-leak PROM, confirmed by intra-amniotic injection of a dye (phenol-sulfonphthalein).

Two cases (27 and 23 weeks of gestation) diagnosed as high-leak PROM by an intra-amniotic dye (PSP) injection method later proved negative on re-testing by the same method, and ended in spontaneous reseal of the membranes. The pregnancies in these cases extended to 36 and 40 weeks of gestation without any eventful signs of infection.