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Varicella-zoster virus retrobulbar optic neuritis in a patient with human immunodeficiency virus.
- Source :
-
American journal of ophthalmology [Am J Ophthalmol] 1996 Oct; Vol. 122 (4), pp. 586-8. - Publication Year :
- 1996
-
Abstract
- Purpose: To determine the cause of bilateral retrobulbar optic neuritis followed by progressive outer retinal necrosis in a patient with human immunodeficiency virus (HIV).<br />Methods: Extensive ophthalmologic, neurologic, infectious disease, rheumatologic, and radiologic examinations were performed.<br />Results: Cerebrospinal fluid samples taken after the onset of bilateral retrobulbar optic neuritis and before the development of clinical progressive outer retinal necrosis disclosed varicella-zoster virus from polymerase chain reaction and viral culture.<br />Conclusion: Ophthalmologists and neurologists should consider varicella-zoster virus optic neuritis as a potential precursor of progressive outer retinal necrosis and as a cause of retrobulbar optic neuritis in patients infected with HIV.
- Subjects :
- AIDS-Related Opportunistic Infections drug therapy
AIDS-Related Opportunistic Infections pathology
Adult
Antiviral Agents therapeutic use
Cerebrospinal Fluid virology
DNA, Viral analysis
Female
Herpes Zoster Ophthalmicus drug therapy
Herpes Zoster Ophthalmicus pathology
Herpesvirus 3, Human genetics
Herpesvirus 3, Human isolation & purification
Humans
Magnetic Resonance Imaging
Optic Neuritis drug therapy
Optic Neuritis pathology
Orbit
Polymerase Chain Reaction
Retinal Necrosis Syndrome, Acute etiology
AIDS-Related Opportunistic Infections etiology
Eye Infections, Viral drug therapy
Eye Infections, Viral etiology
Eye Infections, Viral pathology
Herpes Zoster Ophthalmicus etiology
Optic Neuritis etiology
Subjects
Details
- Language :
- English
- ISSN :
- 0002-9394
- Volume :
- 122
- Issue :
- 4
- Database :
- MEDLINE
- Journal :
- American journal of ophthalmology
- Publication Type :
- Academic Journal
- Accession number :
- 8862063
- Full Text :
- https://doi.org/10.1016/s0002-9394(14)72127-0