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[Formation of a new antibiotic, nocamycin, by a culture of Nocardiopsis syringae sp. nov].

Authors :
Gauze GF
Sveshnikova MA
Ukholina RS
Komarova GN
Bazhanov VS
Source :
Antibiotiki [Antibiotiki] 1977 Jun; Vol. 22 (6), pp. 483-6.
Publication Year :
1977

Abstract

A culture of a new actinomycetous species, Nocardiopsis syrinage was isolated from a soil sample. The antibiotic produced by it was named nocamycin. It accumulated in the culture fluid on cultivation of the organism in a nutrient medium containing soybean meal, glycerin, sodium chloride and calcium carbonate. Crystalline nocamycin had an antitumor effect. In inhibited by 72--73 per cent the development of an intraperitoneally implanted lymphadenosis of strain NK/LI in mice.

Details

Language :
Russian
ISSN :
0003-5637
Volume :
22
Issue :
6
Database :
MEDLINE
Journal :
Antibiotiki
Publication Type :
Academic Journal
Accession number :
883793