Right-left asymmetry of D1- and D2-receptor density is lost in the basal ganglia of old rats.

In the present study a left-right asymmetry in both D1- and D2-receptor density in the caudate-putamen nucleus is shown and a lateralisation of D2-receptor distribution in the accunbens nucleus is also described. In old animals in which D1- and D2-receptors density is decreased, the dopamine receptor asymmetries are lost.