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[Post-actinic retrobulbar optic neuropathy].

Authors :
Borruat FX
Schatz NJ
Glaser JS
Source :
Klinische Monatsblatter fur Augenheilkunde [Klin Monbl Augenheilkd] 1996 May; Vol. 208 (5), pp. 381-4.
Publication Year :
1996

Abstract

Background: Radiation optic neuropathy (RON) is a rare, unpredictable, late complication of radiotherapy secondary to obliterative endarteritis. Tumor recurrence has to be ruled out by a clinical and neuroradiological examination.<br />Methods: Five patients with RON were investigated by magnetic resonance imaging (MRI) during 1992.<br />Results: Radiation-induced lesions of the intracranial visual pathways were easily visible on MRI. Without Gadolinium, a sectorial swelling was detectable, which markedly enhanced with Gadolinium. Intracranial optic nerve was affected in 5/5 cases, optic chiasm in 3/5 cases, and optic tract in 2/5 cases.<br />Conclusions: MRI is the examination of choice when RON is suspected: it will easily delineate the extent of the lesion, and compression/infiltration by a recurrent tumor will be formally ruled out. A segmental swelling of visual pathway with marked Gadolinium enhancement on MRI is highly suggestive of radionecrosis.

Details

Language :
French
ISSN :
0023-2165
Volume :
208
Issue :
5
Database :
MEDLINE
Journal :
Klinische Monatsblatter fur Augenheilkunde
Publication Type :
Academic Journal
Accession number :
8766059
Full Text :
https://doi.org/10.1055/s-2008-1035247