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The influence of Microgynon and Diane-35, two sub-fifty ovulation inhibitors, on voice function in women.
- Source :
-
Contraception [Contraception] 1995 Dec; Vol. 52 (6), pp. 343-8. - Publication Year :
- 1995
-
Abstract
- The early days of oral contraceptives showed some evidence that these medications may have caused undesirable side effects on the voice, mainly in terms of virilization. In a random study carried out at the university hospitals of Jena and Berlin (Charité), two more recent drugs were tested in this regard, one containing cyproterone acetate (Diane-35) and the other one levonorgestrel (Microgynon), both from Schering. Ninety-one patients took part in extensive clinical and instrumental phoniatric investigations of voice function over a period of one year. No significant side effects on the voice could be proven for the two preparations. Gynecological and clinical effects of both Diane-35 and Microgynon were similar during the one-year study period. Women taking Diane-35 had less intracyclic bleedings and amenorrhea. Also, acne was more favorably influenced by Diane-35.
- Subjects :
- Adolescent
Adult
Drug Combinations
Female
Humans
Single-Blind Method
Androgen Antagonists pharmacology
Contraceptives, Oral, Hormonal pharmacology
Cyproterone Acetate pharmacology
Ethinyl Estradiol pharmacology
Ethinyl Estradiol-Norgestrel Combination pharmacology
Ovulation drug effects
Phonation drug effects
Subjects
Details
- Language :
- English
- ISSN :
- 0010-7824
- Volume :
- 52
- Issue :
- 6
- Database :
- MEDLINE
- Journal :
- Contraception
- Publication Type :
- Academic Journal
- Accession number :
- 8749597
- Full Text :
- https://doi.org/10.1016/0010-7824(96)87703-1