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Nucleotide sequence of exons 5 to 9 of the p53 tumour-suppressor gene of the donkey (Equus asinus).

Authors :
Nasir L
Reid SW
Source :
DNA sequence : the journal of DNA sequencing and mapping [DNA Seq] 1995; Vol. 6 (1), pp. 61-3.
Publication Year :
1995

Abstract

The evolutionary conserved region of the equine homologue of the p53 gene from the donkey genome was PCR amplified and cloned. The 1380 bp fragment consisted of exons 5 to 9 and the intervening introns. The exonic and intronic DNA sequences showed a variable but high level of homology with previously published human sequences. The aminoacid sequences corresponding to the evolutionary conserved domains II, III, and V were identical to the human regions, whilst domain IV was 96% homologous.

Details

Language :
English
ISSN :
1042-5179
Volume :
6
Issue :
1
Database :
MEDLINE
Journal :
DNA sequence : the journal of DNA sequencing and mapping
Publication Type :
Academic Journal
Accession number :
8746464
Full Text :
https://doi.org/10.3109/10425179509074702