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Lipoprotein (a) levels in patients undergoing continuous ambulatory peritoneal dialysis.
- Source :
-
Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis [Perit Dial Int] 1996; Vol. 16 Suppl 1, pp. S236-40. - Publication Year :
- 1996
-
Abstract
- Most researchers have found increases of lipoprotein (a) [Lp(a)] in uremic patients, as well as in those undergoing hemodialysis (HD) or continuous ambulatory peritoneal dialysis (CAPD). The mechanisms for this increase remain unclear. We studied 71 patients undergoing CAPD, 48 men and 23 women. According to the time spent on CAPD, the patients were divided into three groups: group 0: 29 patients at the starting off point of dialysis treatment; group I: 22 patients with an average stay of 15.2 months; group II: 20 patients with an average stay of 69.3 months on CAPD. We have only observed significant increases of Lp(a) levels in those patients initiating the dialysis, but no significant differences are found in the other groups undergoing CAPD for longer periods when compared to the control group. We found no significant relation between Lp(a) levels and peritoneal protein loss, and not with absorption of glucose from the dialysate either. We have found a positive and significant correlation between Lp(a) levels and urinary protein loss (r = 0.41; p < 0.001). It is possible that an element associated with proteinuria might have an effect on the metabolism of Lp(a) in CAPD patients.
- Subjects :
- Adult
Aged
Blood Glucose metabolism
Diabetic Nephropathies blood
Diabetic Nephropathies therapy
Female
Humans
Kidney physiopathology
Kidney Failure, Chronic blood
Kidney Failure, Chronic therapy
Male
Middle Aged
Proteinuria blood
Proteinuria therapy
Renal Dialysis
Uremia therapy
Lipoprotein(a) blood
Peritoneal Dialysis, Continuous Ambulatory
Uremia blood
Subjects
Details
- Language :
- English
- ISSN :
- 0896-8608
- Volume :
- 16 Suppl 1
- Database :
- MEDLINE
- Journal :
- Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis
- Publication Type :
- Academic Journal
- Accession number :
- 8728199