[Evaluation of cellular DNA in the study of the relations between fibrocystic disease of the breast and breast cancer].

Two cases of breast carcinoma observed four years after breast biopsy for fibrocystic mastopathy are presented. These two cases have been subjected to microspectrophotometric measurement of cell DNA as an objective test for the evaluation of risk in breast fibrocystic disease. Tissue specimens of the two carcinoma cases showed in some lesions aneuploid DNA, while control groups always showed a typical diploid situation. This technique is suggested when epithelial proliferative pictures in adenose-cystic mastopathy seem to reach serious histopathological levels.