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[Several indicators of lipids, blood hormones and T-cell unit of the immune system in mice with increased body mass at distant periods after local irradiation of the thymus, hypothalamus-hypophysis and gonads].
- Source :
-
Radiatsionnaia biologiia, radioecologiia [Radiats Biol Radioecol] 1996 Mar-Apr; Vol. 36 (2), pp. 278-83. - Publication Year :
- 1996
-
Abstract
- In hybrid mice it was shown that the local irradiation of zones of thymus, hypothalamus-hypophysis (0.5, 1 and 10 Gy in both cases) and gonads (10 Gy) resulted in significant increase in weight at long terms after irradiation. In animals with increased weight the amount of lipids raised, balance of hormones and state of thymus-dependent unit of immune system changed, and exterior symptoms of early aging were observed. After irradiation of spleen and thigh muscles (10 Gy in both cases) all indices at the same period corresponded to age control.
- Subjects :
- Aging
Animals
Growth Hormone blood
Hydrocortisone blood
Male
Mice
Radiation Dosage
Spleen radiation effects
Weight Gain
Hormones blood
Hypothalamus radiation effects
Lipids blood
Pituitary Gland radiation effects
T-Lymphocytes radiation effects
Testis radiation effects
Thymus Gland radiation effects
Subjects
Details
- Language :
- Russian
- ISSN :
- 0869-8031
- Volume :
- 36
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Radiatsionnaia biologiia, radioecologiia
- Publication Type :
- Academic Journal
- Accession number :
- 8673224