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Squamous cell carcinoma arising in dermoid cyst.
- Source :
-
European journal of gynaecological oncology [Eur J Gynaecol Oncol] 1996; Vol. 17 (2), pp. 144-7. - Publication Year :
- 1996
-
Abstract
- Since malignant transformation in a dermoid cyst is extremely rare, the clinicopathological characteristics of patients with squamous carcinoma arising in dermoid cyst are evaluated in the hope of offering a more rational therapy. Our first patient was lost to follow-up after surgery. In the second patient, with a gross stage III disease, after extensive surgery and multiagent chemotherapy we were able to achieve a remission period of 42 months. In the third patient with pelvic lymph node metastases, adjuvant radiation and chemotherapy was administered following surgical staging. She was free of disease 6 months after surgery. Malignant transformation in a dermoid cyst is a rare complication observed especially in older age groups. Thus, a frozen section in these decades may improve detection of this complication allowing a more accurate staging. Although poor prognosis is reported, an aggressive approach with cisplatinum based chemotherapy and radiation and even with secondary cytoreduction, long-term remission may be achieved.
Details
- Language :
- English
- ISSN :
- 0392-2936
- Volume :
- 17
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- European journal of gynaecological oncology
- Publication Type :
- Academic Journal
- Accession number :
- 8654472