FTY720, a novel immunosuppressant possessing unique mechanisms. I. Prolongation of skin allograft survival and synergistic effect in combination with cyclosporine in rats.

Subjects

Subjects :

Animals
Drug Synergism
Drug Therapy, Combination
Fingolimod Hydrochloride
Interleukin-2 biosynthesis
Major Histocompatibility Complex
Male
Rats
Rats, Inbred F344
Rats, Inbred Lew
Rats, Inbred Strains
Sphingosine analogs & derivatives
Spleen
T-Lymphocytes drug effects
T-Lymphocytes immunology
Transplantation, Homologous
Cyclosporine therapeutic use
Graft Survival drug effects
Immunosuppressive Agents therapeutic use
Propylene Glycols therapeutic use
Skin Transplantation immunology

Details

Language :

English

ISSN :

0041-1345

Volume :

28

Issue :

2

Database :

MEDLINE

Journal :

Transplantation proceedings

Publication Type :

Academic Journal

Accession number :

8623225