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Human psychopharmacology of hoasca, a plant hallucinogen used in ritual context in Brazil.
- Source :
-
The Journal of nervous and mental disease [J Nerv Ment Dis] 1996 Feb; Vol. 184 (2), pp. 86-94. - Publication Year :
- 1996
-
Abstract
- A multinational, collaborative, biomedical investigation of the effects of hoasca (ayahuasca), a potent concoction of plant hallucinogens, was conducted in the Brazilian Amazon during the summer of 1993. This report describes the psychological assessment of 15 long-term members of a syncretic church that utilizes hoasca as a legal, psychoactive sacrament as well as 15 matched controls with no prior history of hoasca ingestion. Measures administered to both groups included structured psychiatric diagnostic interviews, personality testing, and neuropsychological evaluation. Phenomenological assessment of the altered state experience as well as semistructured and open-ended life story interviews were conducted with the long-term use hoasca group, but not the hoasca-naive control group. Salient findings included the remission of psychopathology following the initiation of hoasca use along with no evidence of personality or cognitive deterioration. Overall assessment revealed high functional status. Implications of this unusual phenomenon and need for further investigation are discussed.
- Subjects :
- Adult
Brazil epidemiology
Cognition drug effects
Harmine pharmacology
Humans
Magic
Male
Medicine, Traditional
Mental Disorders diagnosis
Mental Disorders epidemiology
Middle Aged
Neuropsychological Tests
Personality drug effects
Psychiatric Status Rating Scales
Substance-Related Disorders diagnosis
Substance-Related Disorders psychology
Tea
Verbal Learning drug effects
Hallucinogens pharmacology
Plants, Medicinal
Religion and Medicine
Subjects
Details
- Language :
- English
- ISSN :
- 0022-3018
- Volume :
- 184
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- The Journal of nervous and mental disease
- Publication Type :
- Academic Journal
- Accession number :
- 8596116
- Full Text :
- https://doi.org/10.1097/00005053-199602000-00004