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Susceptibility to development of central adiposity among populations.
- Source :
-
Obesity research [Obes Res] 1995 Sep; Vol. 3 Suppl 2, pp. 179S-186S. - Publication Year :
- 1995
-
Abstract
- There is good evidence that central (visceral) adiposity is important in the development of the insulin resistance or metabolic syndrome (obesity, hyperinsulinemia, dyslipidemia, glucose intolerance, hypertension, and coronary heart disease). It is proposed that some non-Caucasian populations are especially susceptible to development of this syndrome, and that lifestyle changes may play important etiologic roles. We postulate that this is due to the presence in these populations of a genetic predisposition to weight gain, perhaps related to a "thrifty" genotype, leading to the concentration of weight gain in visceral fat depots, when there is exposure to conditions associated with westernization.
- Subjects :
- Adipose Tissue pathology
Adult
Aged
Asia epidemiology
Asian genetics
Body Composition genetics
Body Constitution
Causality
Coronary Disease epidemiology
Coronary Disease physiopathology
Diabetes Mellitus epidemiology
Diabetes Mellitus physiopathology
Diabetes, Gestational epidemiology
Disease Susceptibility
Female
Humans
Hypertension epidemiology
Hypertension physiopathology
Japan epidemiology
Male
Middle Aged
Obesity ethnology
Obesity genetics
Pacific Islands epidemiology
Pregnancy
Syndrome
Washington epidemiology
Weight Gain genetics
Body Composition physiology
Obesity epidemiology
Weight Gain physiology
Subjects
Details
- Language :
- English
- ISSN :
- 1071-7323
- Volume :
- 3 Suppl 2
- Database :
- MEDLINE
- Journal :
- Obesity research
- Publication Type :
- Academic Journal
- Accession number :
- 8581774
- Full Text :
- https://doi.org/10.1002/j.1550-8528.1995.tb00461.x