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Medicinal foodstuffs. I. Hypoglycemic constituents from a garnish foodstuff "taranome," the young shoot of Aralia elata SEEM.: elatosides G, H, I, J, and K.
- Source :
-
Chemical & pharmaceutical bulletin [Chem Pharm Bull (Tokyo)] 1995 Nov; Vol. 43 (11), pp. 1878-82. - Publication Year :
- 1995
-
Abstract
- Five new saponins named elatosides G, H, I, J, and K were isolated from a garnish foodstuff "Taranome," the young shoot of Aralia elata SEEM., together with hederagenin-3-O-glucuronopyranoside and elatoside C. Their chemical structures were elucidated on the basis of chemical and physicochemical evidence. Elatosides G, H, and I were found to exhibit potent hypoglycemic activity in the oral glucose tolerance test in rats.
- Subjects :
- Analysis of Variance
Animals
Chemical Fractionation
Chromatography, High Pressure Liquid
Glucose Tolerance Test
Hypoglycemic Agents chemistry
Hypoglycemic Agents toxicity
Magnetic Resonance Spectroscopy
Male
Rats
Rats, Wistar
Saponins chemistry
Spectrometry, Mass, Fast Atom Bombardment
Structure-Activity Relationship
Hypoglycemic Agents isolation & purification
Oleanolic Acid analogs & derivatives
Saponins isolation & purification
Subjects
Details
- Language :
- English
- ISSN :
- 0009-2363
- Volume :
- 43
- Issue :
- 11
- Database :
- MEDLINE
- Journal :
- Chemical & pharmaceutical bulletin
- Publication Type :
- Academic Journal
- Accession number :
- 8575028
- Full Text :
- https://doi.org/10.1248/cpb.43.1878