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[Sero-epidemiology of hepatitis A: alcoholic patients are a group at risk].
- Source :
-
Gastroenterologie clinique et biologique [Gastroenterol Clin Biol] 1995 Oct; Vol. 19 (10), pp. 751-5. - Publication Year :
- 1995
-
Abstract
- Objectives: The possibility of "community-acquired" viral infection has been suggested in alcoholics. In order to assess this hypothesis, we evaluated the prevalence of antibodies against hepatitis A virus, a oro-fecally transmitted virus, in heavy drinkers.<br />Patients and Methods: We retrospectively studied 258 heavy drinkers, 188 males and 70 females, divided into sub-groups of increasing age, and compared them to 277 similarly classified blood donors.<br />Results: The prevalence of serum anti-hepatitis A antibodies was significantly higher in alcoholics than in controls (64.7 vs 52.3%, P < 0.01). The difference was particularly marked in patients younger than 45 years old (56.2 vs 39.1%, P < 0.01). In the alcoholics, there was no correlation between the prevalence of anti-hepatitis A antibodies and the socioeconomic level, the quantity of alcohol ingested, or the severity of the underlying liver disease.<br />Conclusion: These results suggest that alcoholism is, per se, a risk factor for viral infections.
- Subjects :
- Adolescent
Adult
Aged
Alcoholism complications
Female
Hepatitis A immunology
Hepatitis B epidemiology
Hepatitis B Antibodies analysis
Hepatitis C epidemiology
Hepatitis C Antibodies analysis
Humans
Male
Middle Aged
Prevalence
Reference Values
Retrospective Studies
Risk Factors
Socioeconomic Factors
Hepatitis A epidemiology
Hepatitis Antibodies analysis
Liver Cirrhosis, Alcoholic virology
Liver Diseases, Alcoholic virology
Subjects
Details
- Language :
- French
- ISSN :
- 0399-8320
- Volume :
- 19
- Issue :
- 10
- Database :
- MEDLINE
- Journal :
- Gastroenterologie clinique et biologique
- Publication Type :
- Academic Journal
- Accession number :
- 8566556