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Cutaneous response to dinitrochlorobenzene in patients with genito-urinary cancers.
- Source :
-
Biomedicine / [publiee pour l'A.A.I.C.I.G.] [Biomedicine] 1977 Jan 31; Vol. 27 (1), pp. 43-7. - Publication Year :
- 1977
-
Abstract
- The aim of the present study is to analyse the response in patients with cancer of the urogenital region to a primary antigen 2-4 dinitrochlorobenzene (DNCB). A total of 69 patients with neoplastic disease were studied (13 cases with kidney cancer, 34 cases with bladder cancer, 13 cases with prostatic cancer, 5 cases with testicular cancer, one case with penis cancer, and 3 cases with cancer of the cervix, comparatively with 13 patients with non-malignant urological diseases. Whereas in the control group, 78% of the patients gave a positive skin reaction to DNCB, 15% of the patients with kidney cancer, 56% of the patients with bladder cancer, 69% of the patients with prostatic cancer and 60% of the patients with testicular cancer gave a positive reaction. If we consider the stages of the disease, the reaction was positive, in 91% of bladder cancer at stage I and in 47% at stages II and III in 100% of prostatic cancer at stage I and in 62% at stages II and III, in 60% of testicular cancer at stage IV (but 100% of seminomas and 0% of dysembryomas have a positive reaction). It would therefore seem that a correlation exists between the degree of the extension of the disease and the skin reaction to DNCB.
- Subjects :
- Female
Humans
Kidney Neoplasms immunology
Male
Penile Neoplasms immunology
Prostatic Neoplasms immunology
Testicular Neoplasms immunology
Urinary Bladder Neoplasms immunology
Uterine Neoplasms immunology
Dinitrochlorobenzene
Immunity, Cellular
Nitrobenzenes
Skin immunology
Urogenital Neoplasms immunology
Subjects
Details
- Language :
- English
- ISSN :
- 0300-0893
- Volume :
- 27
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Biomedicine / [publiee pour l'A.A.I.C.I.G.]
- Publication Type :
- Academic Journal
- Accession number :
- 856314