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Cutaneous response to dinitrochlorobenzene in patients with genito-urinary cancers.

Authors :
Duclos H
Schwarzenberg L
Duclos SH
Hugues H
Kuss R
Source :
Biomedicine / [publiee pour l'A.A.I.C.I.G.] [Biomedicine] 1977 Jan 31; Vol. 27 (1), pp. 43-7.
Publication Year :
1977

Abstract

The aim of the present study is to analyse the response in patients with cancer of the urogenital region to a primary antigen 2-4 dinitrochlorobenzene (DNCB). A total of 69 patients with neoplastic disease were studied (13 cases with kidney cancer, 34 cases with bladder cancer, 13 cases with prostatic cancer, 5 cases with testicular cancer, one case with penis cancer, and 3 cases with cancer of the cervix, comparatively with 13 patients with non-malignant urological diseases. Whereas in the control group, 78% of the patients gave a positive skin reaction to DNCB, 15% of the patients with kidney cancer, 56% of the patients with bladder cancer, 69% of the patients with prostatic cancer and 60% of the patients with testicular cancer gave a positive reaction. If we consider the stages of the disease, the reaction was positive, in 91% of bladder cancer at stage I and in 47% at stages II and III in 100% of prostatic cancer at stage I and in 62% at stages II and III, in 60% of testicular cancer at stage IV (but 100% of seminomas and 0% of dysembryomas have a positive reaction). It would therefore seem that a correlation exists between the degree of the extension of the disease and the skin reaction to DNCB.

Details

Language :
English
ISSN :
0300-0893
Volume :
27
Issue :
1
Database :
MEDLINE
Journal :
Biomedicine / [publiee pour l'A.A.I.C.I.G.]
Publication Type :
Academic Journal
Accession number :
856314