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Efficacy of ICAM-1 antisense oligonucleotide in pancreatic islet transplantation.
- Source :
-
Transplantation proceedings [Transplant Proc] 1995 Dec; Vol. 27 (6), pp. 3214. - Publication Year :
- 1995
-
Abstract
- Significant islet allograft prolongation was achieved by ICAM-1/LFA-1 blockade. ICAM-1 antisense oligonucleotide IP-3082 was effective in improving islet function as well as prolonging graft survival.
- Subjects :
- Animals
Antibodies, Monoclonal pharmacology
Blood Glucose metabolism
Diabetes Mellitus, Experimental surgery
Graft Survival
Intercellular Adhesion Molecule-1 genetics
Islets of Langerhans Transplantation immunology
Islets of Langerhans Transplantation physiology
Lymphocyte Function-Associated Antigen-1 immunology
Mice
Mice, Inbred C3H
Mice, Inbred C57BL
Transplantation, Homologous
Intercellular Adhesion Molecule-1 immunology
Islets of Langerhans Transplantation methods
Oligonucleotides, Antisense pharmacology
Subjects
Details
- Language :
- English
- ISSN :
- 0041-1345
- Volume :
- 27
- Issue :
- 6
- Database :
- MEDLINE
- Journal :
- Transplantation proceedings
- Publication Type :
- Academic Journal
- Accession number :
- 8539920