Megakaryocytes in the acute stage of experimental hemorrhagic shock. Part III. Histomorphometrical evaluation of megakaryocytes.

The authors presented the morphometrical evaluation of the bone marrow MK in rats in the acute stage of experimental hemorrhagic shock. The experiments used a semiautomatic computer programme. The total number of MK per 1 mm2 of the bone marrow was analysed with regard to various morphological forms of MK, their surface area, shape disorders, nuclear-cytoplasmic ratio and cluster forms. A considerable shift was observed in the MK parameters examined, suggesting a significant effect of hemorrhagic shock upon megakaryocytopoiesis.