Glutathion S-transferase activity and DDT-susceptibility of Malaysian mosquitos.

Authors :: Lee HL
Chong WL
Source :: The Southeast Asian journal of tropical medicine and public health [Southeast Asian J Trop Med Public Health] 1995 Mar; Vol. 26 (1), pp. 164-7.
Publication Year :: 1995
Abstract: Comparative DDT-susceptibility status and glutathion s-transferase (GST) activity of Malaysian Anopheles maculatus, Culex quinquefasciatus and Aedes aegypti was investigated to ascertain the role of this enzyme in DDT resistance. The standardised WHO dose-mortality bioassay tests were used to determine DDT susceptibility in these mosquitos, whilst GST microassay (Brogdon and Barber, 1990) was conducted to measure the activity of this enzyme in mosquito homogenate. It appeared that DDT susceptibility status of Malaysian mosquitos was not correlated with GST activity.

Subjects :: Animals
Culicidae drug effects
Larva drug effects
Malaysia
Culicidae enzymology
DDT pharmacology
Glutathione Transferase metabolism
Insecticide Resistance physiology
Insecticides pharmacology

Language :: English
ISSN :: 0125-1562
Volume :: 26
Issue :: 1
Database :: MEDLINE
Journal :: The Southeast Asian journal of tropical medicine and public health
Publication Type :: Academic Journal
Accession number :: 8525405

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