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NMR studies on penicillins: hydrogen bonding, self-association and micellar solutions of cloxacillin Na-salt in D2O.

Authors :
Kupka T
Dziegielewski JO
Pasterna G
Source :
Journal of pharmaceutical and biomedical analysis [J Pharm Biomed Anal] 1993 Feb; Vol. 11 (2), pp. 103-16.
Publication Year :
1993

Abstract

Self-association and formation of micellar solutions of cloxacillin sodium salt (CLO-Na) dissolved in heavy water have been investigated by NMR-spectroscopy. Concentration and temperature dependence of proton and carbon chemical shifts of cloxacillin-Na in D2O is presented and certain 1H and 13C NMR line assignments have been substantiated.

Details

Language :
English
ISSN :
0731-7085
Volume :
11
Issue :
2
Database :
MEDLINE
Journal :
Journal of pharmaceutical and biomedical analysis
Publication Type :
Academic Journal
Accession number :
8504181
Full Text :
https://doi.org/10.1016/0731-7085(93)80130-s