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Respiratory status and diuresis following treatment with dexamethasone.
- Source :
-
Early human development [Early Hum Dev] 1993 Mar; Vol. 32 (2-3), pp. 87-91. - Publication Year :
- 1993
-
Abstract
- The effect of dexamethasone therapy on fluid balance, lung function and requirement for respiratory support has been assessed. Ten premature infants were studied, they had a median gestational age of 28 weeks. None of the infants had any improvement in the respiratory status for 48 h prior to commencing dexamethasone. Fluid balance, pulmonary function and requirement for respiratory support were measured 12 h prior to and for 36 h after receiving dexamethasone. There were no significant changes in fluid input over the study period, but urine output increased significantly after 12 h of dexamethasone therapy (P < 0.02). Compliance of the respiratory system only significantly improved after 36 h of dexamethasone therapy (P < 0.03), this was associated with a significant change in the inspired oxygen concentration (P < 0.05). We conclude that the improvement in respiratory status resulting from dexamethasone therapy is preceded by a diuresis.
Details
- Language :
- English
- ISSN :
- 0378-3782
- Volume :
- 32
- Issue :
- 2-3
- Database :
- MEDLINE
- Journal :
- Early human development
- Publication Type :
- Academic Journal
- Accession number :
- 8486124
- Full Text :
- https://doi.org/10.1016/0378-3782(93)90002-c