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Dominant lethal studies with technical chlordane, HCS-3260, and heptachlor: heptachlor epoxide.
- Source :
-
Journal of toxicology and environmental health [J Toxicol Environ Health] 1977 Jan; Vol. 2 (3), pp. 547-55. - Publication Year :
- 1977
-
Abstract
- Male albino mice in groups of eight were each given single doses, either by gavage or by intraperitoneal injection, of either technical chlordane (50 or 100 mg/kg), HCS-3260 (50 or 100 mg/kg), or heptachlor:heptachlor epoxide (25:75) (7.5 or 15 mg/kg). The males were subsequently mated with three untreated females for six consecutive weeks. No dominant lethal changes among females that had mated with the treated males were produced.
- Subjects :
- Animals
Chlordan analogs & derivatives
Chlordan toxicity
Diet
Embryo, Mammalian drug effects
Female
Heptachlor toxicity
Heptachlor Epoxide toxicity
Male
Pregnancy
Rats
Chlordan pharmacology
Genes, Dominant drug effects
Genes, Lethal drug effects
Heptachlor analogs & derivatives
Heptachlor pharmacology
Heptachlor Epoxide pharmacology
Mutagens
Subjects
Details
- Language :
- English
- ISSN :
- 0098-4108
- Volume :
- 2
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- Journal of toxicology and environmental health
- Publication Type :
- Academic Journal
- Accession number :
- 846003
- Full Text :
- https://doi.org/10.1080/15287397709529455