[Clinical evaluation of cefpodoxime in respiratory tract infections].

Authors :: Fukuhara H
Irabu Y
Kakazu T
Nakamura H
Shigeno Y
Saito A
Owan T
Oshiro H
Miyaguni T
Nakasone K
Source :: The Japanese journal of antibiotics [Jpn J Antibiot] 1993 Jan; Vol. 46 (1), pp. 53-9.
Publication Year :: 1993
Abstract: Cefpodoxime (CPDX-PR) was evaluated clinically in respiratory tract infections. The results obtained are summarized as follows; 1. The total number of the patients who were treated with CPDX-PR was 61, out of whom 53 cases were evaluated for clinical efficacy and 55 cases were investigated for the safety of the drug. CPDX-PR was given orally twice a day at 100-200 mg for 5-21 days. 2. Clinical efficacies were excellent in 9 patients, good in 36, fair in 4 and poor in 4. The overall clinical efficacy was 84.9%. In particular, CPDX-PR showed satisfactory efficacy for acute respiratory infections and mild chronic respiratory infections, with efficacy rates of 88.6% (31/35) and 100% (8/8), respectively. 3. No adverse reactions was observed, but slight and transient elevation of BUN was noted. In conclusion, it has been confirmed that CPDX-PR is an excellent and safe drug for the treatment of the respiratory tract infections.