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[Relationship between the skin test and the specific IgE (radio-allergo-sorbens test) in the diagnosis of inhalative allergies].
- Source :
-
Zeitschrift fur Hautkrankheiten [Z Hautkr] 1977 Feb 15; Vol. 52 (4), pp. 109-16. - Publication Year :
- 1977
-
Abstract
- Immediate-type reactions such as asthma, pollinosis and several forms of urticaria can be regarded as type I reactions according to Coombs and Gell. Primary these diseases are caused by the immune globulin E. As skin testing is accompanied by numerous failors, there is a real possibility in increasing the diagnostic relevance by measurement of the specific IgE in serum (Radio-Allergo-Sorbens-Test = RAST; Phadebas-RAST -- Pharmacia Uppsala). There are often found divergent results and therefore this investigation was started. 1357 RAST-results (530 patients) were compared with skin tests in order to investigate the concordance of the two test-methods. The statistical analysis is performed wit "4-square-Chi2". Very good correspondence could be calculated for the pollens of Festuca elatior, Poa pratensis, horse-epithelium and housedustmite (1 0/00O significancy). 1 0/0 significancy was found for catepithelium and 5 0/0 for Birch-pollen. The advantages and the disadventages of RAST are discussed.
Details
- Language :
- German
- ISSN :
- 0301-0481
- Volume :
- 52
- Issue :
- 4
- Database :
- MEDLINE
- Journal :
- Zeitschrift fur Hautkrankheiten
- Publication Type :
- Academic Journal
- Accession number :
- 842065