(E)-3-[[[[6-(2-carboxyethenyl)-5-[[8-(4- methoxyphenyl)octyl]oxy]-2-pyridinyl]-methyl]thio]methyl]benzoic acid: a novel high-affinity leukotriene B4 receptor antagonist.

Authors :: Daines RA
Chambers PA
Pendrak I
Jakas DR
Sarau HM
Foley JJ
Schmidt DB
Griswold DE
Martin LD
Tzimas MN
Source :: Journal of medicinal chemistry [J Med Chem] 1993 Sep 03; Vol. 36 (18), pp. 2703-5.
Publication Year :: 1993

Subjects :: Animals
Benzoates chemical synthesis
Benzoates therapeutic use
Calcium metabolism
Humans
Inflammation drug therapy
Leukotriene B4 pharmacology
Mice
Molecular Structure
Neutrophils drug effects
Neutrophils metabolism
Pyridines chemical synthesis
Pyridines therapeutic use
Anti-Inflammatory Agents, Non-Steroidal chemical synthesis
Benzoates pharmacology
Pyridines pharmacology
Receptors, Leukotriene B4 antagonists & inhibitors

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