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Effect of Helicobacter pylori colonization on quantitative distribution of antral G-cells in apparently healthy subjects and in duodenal ulcer patients. A morphometric study.
- Source :
-
The Italian journal of gastroenterology [Ital J Gastroenterol] 1993 Jul; Vol. 25 (6), pp. 318-20. - Publication Year :
- 1993
-
Abstract
- To investigate whether antral colonization by Helicobacter pylori (Hp) modifies gastrin-cell population, the number of G-cells was evaluated in antral biopsy specimens from 22 apparently healthy subjects and from 48 duodenal ulcer patients using a morphometric method. The level of serum immunoreactive gastrin in a sample of fasting serum obtained at the time of biopsy was also measured. In healthy subjects the G-cell count (evaluated according to G/I index) and the serum gastrin levels were not significantly different than those found in duodenal ulcer patients. When the antral colonization by Hp was assessed, we found that, both controls and duodenal ulcer Hp-positive patients had a mean G-cell count and fasting serum gastrin levels not significantly higher than in patients without Hp.
- Subjects :
- Adult
Biopsy
Cell Count
Chronic Disease
Duodenal Ulcer blood
Duodenal Ulcer pathology
Female
Gastric Mucosa metabolism
Gastric Mucosa pathology
Gastrins blood
Gastrins metabolism
Gastritis blood
Gastritis microbiology
Gastritis pathology
Humans
Male
Pyloric Antrum
Duodenal Ulcer microbiology
Gastric Mucosa microbiology
Helicobacter pylori isolation & purification
Subjects
Details
- Language :
- English
- ISSN :
- 0392-0623
- Volume :
- 25
- Issue :
- 6
- Database :
- MEDLINE
- Journal :
- The Italian journal of gastroenterology
- Publication Type :
- Academic Journal
- Accession number :
- 8400368