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Relation between exposure related indices and neurological and neurophysiological effects in workers previously exposed to mercury vapour.
- Source :
-
British journal of industrial medicine [Br J Ind Med] 1993 Aug; Vol. 50 (8), pp. 736-44. - Publication Year :
- 1993
-
Abstract
- A cross sectional study of aspects of their neurology was carried out on 77 chloralkali workers previously exposed to mercury (Hg) vapour and compared with 53 age matched referents. The chloralkali workers had been exposed for an average of 7.9 years at a concentration of 59 micrograms Hg/m3 in the working atmosphere. The individual mean urinary concentration of Hg for each year of exposure was 531 nmol Hg/1. On average the exposure had ceased 12.3 years before the examinations. Both the median sensory nerve conduction velocity and the amplitude of the sural nerve were associated with measures of cumulative exposure to Hg. An association was also found between years since first exposure to Hg and aspects of the visual evoked response. Previously exposed subjects with postural tremor or impaired coordination also had alterations in visual evoked response. These results may indicate an effect of previous exposure to mercury vapour on the nervous system, possibly in the visual pathway, cerebellum, and the peripheral sensory nerves.
- Subjects :
- Adult
Cross-Sectional Studies
Evoked Potentials, Auditory, Brain Stem drug effects
Evoked Potentials, Somatosensory drug effects
Evoked Potentials, Visual drug effects
Humans
Male
Median Nerve physiopathology
Middle Aged
Neural Conduction physiology
Occupational Diseases physiopathology
Peripheral Nervous System Diseases physiopathology
Psychomotor Performance drug effects
Sural Nerve physiopathology
Time Factors
Tremor chemically induced
Mercury adverse effects
Occupational Diseases chemically induced
Occupational Exposure adverse effects
Peripheral Nervous System Diseases chemically induced
Subjects
Details
- Language :
- English
- ISSN :
- 0007-1072
- Volume :
- 50
- Issue :
- 8
- Database :
- MEDLINE
- Journal :
- British journal of industrial medicine
- Publication Type :
- Academic Journal
- Accession number :
- 8398861
- Full Text :
- https://doi.org/10.1136/oem.50.8.736