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Fructosamine. A new parameter for diagnosis and metabolic control in diabetic dogs and cats.
- Source :
-
Journal of veterinary internal medicine [J Vet Intern Med] 1993 May-Jun; Vol. 7 (3), pp. 177-82. - Publication Year :
- 1993
-
Abstract
- Fructosamines are glycated serum proteins that, depending on their life span, reflect glycemic control over the previous 2 to 3 weeks. The nitroblue tetrazolium reduction method adapted to auto analysis appeared to be a practical means to assay fructosamine quickly, economically, and accurately. The upper limit of the reference range is 374 mumol/L in dogs (95% percentile) and 340 mumol/L in cats (95% percentile). Newly diagnosed diabetic dogs and cats that had not undergone previous insulin therapy had significantly higher fructosamine concentrations than nondiabetic animals. In diabetic dogs that were receiving insulin therapy, the fructosamine test reflected the glycemic state far more accurately than did individual blood glucose measurements. Animals with satisfactory metabolic control revealed fructosamine concentrations within the reference range, whereas fructosamine concentrations above 400 mumol/L indicated insufficient metabolic control. On the basis of fructosamine concentrations, cats with a transitory hyperglycemia and cats with diabetes mellitus were differentiated. The fructosamine test is a valuable parameter for the diagnosis and metabolic control of diabetes mellitus in dogs and cats.
- Subjects :
- Animals
Blood Glucose analysis
Cat Diseases blood
Cats blood
Diabetes Mellitus blood
Diabetes Mellitus diagnosis
Diagnosis, Differential
Dog Diseases blood
Dogs blood
Female
Fructosamine
Hyperglycemia diagnosis
Hyperglycemia veterinary
Male
Reference Standards
Cat Diseases diagnosis
Diabetes Mellitus veterinary
Dog Diseases diagnosis
Hexosamines blood
Subjects
Details
- Language :
- English
- ISSN :
- 0891-6640
- Volume :
- 7
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- Journal of veterinary internal medicine
- Publication Type :
- Academic Journal
- Accession number :
- 8331612
- Full Text :
- https://doi.org/10.1111/j.1939-1676.1993.tb03183.x