Case reports of malformations associated with maternal diabetes: history and critique.

Authors :: Kalter H
Source :: Clinical genetics [Clin Genet] 1993 Apr; Vol. 43 (4), pp. 174-9.
Publication Year :: 1993
Abstract: Several malformations and malformation complexes have been alleged to be associated with maternal type 1 diabetes mellitus: in particular, sacral dysplasia, caudal regression/sirenomelia, femoral dysplasia, and holoprosencephaly. For some of the malformations the claim rests on case material, and for others on theoretical considerations. The history and evolution of these ideas are presented.

Subjects :: Ectromelia etiology
Facial Bones abnormalities
Female
Femur abnormalities
Holoprosencephaly etiology
Humans
Infant, Newborn
Pregnancy
Sacrum abnormalities
Bone Diseases, Developmental etiology
Diabetes Mellitus, Type 1
Pregnancy in Diabetics

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