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Intestinal and hepatic nitrogen balance in the rat after the administration of an oral protein load.
- Source :
-
The British journal of nutrition [Br J Nutr] 1993 May; Vol. 69 (3), pp. 733-42. - Publication Year :
- 1993
-
Abstract
- The fate of a small oral dose of protein given to overnight-starved rats was studied. After 3 h, 62% of the protein amino acids had been absorbed. Most of the absorbed N went into the bloodstream through the portal in the form of amino acids, but urea and ammonia were also present. About one-quarter of all absorbed N was carried as lymph amino acids. The liver was able to take all portal free ammonia and a large proportion of portal amino acids, releasing urea. The hepatic N balance was negative, indicating active proteolysis and net loss of liver protein.
- Subjects :
- Amino Acids metabolism
Ammonia metabolism
Animals
Dietary Proteins administration & dosage
Intestinal Absorption physiology
Lymph metabolism
Male
Portal System physiology
Rats
Rats, Wistar
Time Factors
Urea metabolism
Dietary Proteins metabolism
Intestinal Mucosa metabolism
Liver metabolism
Nitrogen metabolism
Subjects
Details
- Language :
- English
- ISSN :
- 0007-1145
- Volume :
- 69
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- The British journal of nutrition
- Publication Type :
- Academic Journal
- Accession number :
- 8329349
- Full Text :
- https://doi.org/10.1079/bjn19930074